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氨基核苷嘌呤霉素

目录号:

P1343

所属分类:

核苷衍生物

具有重要生物活性的衍生物

应用与生物特性:

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产品详情


Catalog No.

P1343

Name

3’-Amino-3’-deoxy-N6,N6-dimethyl adenosine; 

Synonyms

puromycin amino nucleoside (PAN), NSC 3056 

中文名称

氨基核苷嘌呤霉素

Formula

C12H18N6O3

FW

294.31

CAS No.

58-60-6

Purity

≥ 97%

Property

white or off-white solid

Solubility: soluble in water

Storage: sealed container at room temperature

Package

Packed as desired

Classification

Nucleoside Derivatives; Biologically Important Derivatives

Application & Biological Property

It ia s glomerular epithelial cell toxin and podocyte toxin. It is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models. It induces apoptosis, and also a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase. It also induces secretion of cell migrasome.

References

 

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