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3’-叠氮-2’,3’-双脱氧尿苷

目录号:

P1312

所属分类:

核苷衍生物

应用与生物特性:

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产品详情


Catalog No.

P1312

Name

3’-Azido-2’,3’-dideoxy uridine

Synonyms

AZDU, AzddU, Navuridine

中文名称

3’-叠氮-2’,3’-双脱氧尿苷

Formula

C9H11N5O4

FW

253.21

CAS No.

84472-85-5

Purity

≥ 97%

Property

white or off-white solid

m. p. 166-167 ℃

Solubility: slightly soluble in DMSO, low solubility in MeOH

Storage: sealed container at room temperature

Package

Packed as desired

Classification

Nucleoside Derivatives; Biologically Important Derivatives

Application & Biological Property

Ziduvudine impurity 8; Used for further modified nucleosides or diagnostic. It is a potent inhibitor of human immunodeficiency virus (HIV) replication in human peripheral blood mononuclear cells (PBMC) with limited toxicity for human bone marrow cells (BMC). The azido group in the molecule can also be used for click chemistry to cyclized with alkynes.

References

 

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