产品详情
|
Catalog No. |
P1176 |
|
Name |
5,6-Dihydro-2’-deoxyuridine |
|
Synonyms |
|
|
中文名称 |
5,6-二氢-2’-脱氧尿苷 |
|
Formula |
C9H14N2O5 |
|
FW |
230.22 |
|
CAS No. |
5626-99-3 |
|
Purity |
≥ 98% |
|
Property |
Appearance and Property: white or off-white solid Solubility: soluble in DMSO, slightly soluble in methanol and water Storage: sealed container at 2–8 °C or at room temperature |
|
Package |
Packed as desired |
|
Classification |
Nucleoside Derivatives |
|
Application & Biological Property |
Modified DNA building block; 5,6-Dihydro-2’-deoxyuridine (dUrd) is a pyrimidine nucleoside that is an important component of modified DNAs. It is phosphorylated by deoxyribonucleoside kinase to form dUrd monophosphate. This compound has been shown to inhibit catalase and other enzymes that hydrolyze hydrogen peroxide, indicating it may have antiviral properties. It was found to inhibit viral growth and terminate replication. It also inhibits the synthesis of DNA by inhibiting oxidative deamination reactions and termini formation in herpes simplex virus type 1. |
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References |
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攀纳燊（河南）医药科学技术有限公司
地址：河南自贸试验区郑州片区（经开）航海路经开第二大街航海东路1291号
邮箱：haifeng.zhang@pannacean.com
电话号码:0371-55159968