2-硫代胞苷
目录号:
所属分类:
核苷衍生物
应用与生物特性:
产品详情
|
Catalog No. |
P1135 |
|
Name |
2-Thiocytidine |
|
Synonyms |
|
|
中文名称 |
2-硫代胞苷 |
|
Formula |
C9H13N3O4S |
|
FW |
259.28 |
|
CAS No. |
13239-97-9 |
|
Purity |
≥ 98% |
|
Property |
Appearance and Property: yellow solid, hygroscopic m. p.: 208–209 °C Solubility: slightly soluble in methanol and water Storage: sealed at 2–8 °C or room temperature |
|
Package |
Packed as desired |
|
Classification |
Nucleoside Derivatives |
|
Application & Biological Property |
Naturally-occurring RNA modified nucleoside s2C for vaccine and cancer research. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. It binds to the catalytic site of ribonucleotide reductase and inhibits the enzyme activity, therefore, inhibiting DNA synthesis. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. 2-Thiocytidine is a potent anti-cancer agent that shows promise in treating several types of cancer, including leukemia, lymphoma, and solid tumors. Through interference with the DNA synthesis process, it effectively halts cancer cell growth, while also demonstrating antiviral activity towards HIV and hepatitis B. |
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